Sands, called up from Triple-A Columbus on Thursday, homered on a 1-2 pitch from Seattle starter Roenis Elias (2-2) in the second inning, driving the ball into the Mariners’ bullpen in left field.
Murphy added his fourth RBI this season as a pinch-hitter, dropping a broken-bat single over the Mariners’ drawn-in infield in the sixth inning.
Robinson Cano, back in the lineup after missing two games with an inner ear infection, homered for the first time since April 14, lining a two-run shot in the third inning. It snapped a string of 171 plate appearances without a homer for Cano, tying the longest streak of his career.
Cleveland’s Shaun Marcum (2-0) lasted just 5 1/3 innings, but did enough to get his second victory in his fourth start. Marcum allowed five hits, but struck out five and gave up only Cano’s homer. Reliever Nick Hagadone, a former University of Washington star, got key outs in the seventh and eighth, including striking out Kyle Seager with the bases loaded to end the seventh. Cody Allen got the final four outs for his 11th save.
Elias was pulled with one out in the sixth after giving up a double to Brandon Moss to put runners at second and third. Elias allowed only five hits but struggled with his control, walking a season-high four, two of whom scored. The 5 1/3 innings pitched was his shortest outing of his seven starts.
Murphy then greeted reliever Tom Wilhelmsen with a broken-bat RBI single.
Seager doubled twice for Seattle, but was stranded at third base both times. He was also thrown out at third trying to advance on Logan Morrison’s base-hit with no outs in the fourth and left the bases loaded in the seventh.
Brad Miller doubled leading off the seventh, snapping an 0-for-23 skid and scored on the next pitch when Dustin Ackley singled up the middle. Austin Jackson reached on a fielder’s choice and advanced to third when Cano singled with two outs. Nelson Cruz walked to load the bases, but Hagadone entered and struck out Seager.
Indians: IF Carlos Santana will rejoin the team and be in the lineup Sunday after staying in Cleveland following the birth of his daughter earlier this week.
Mariners: LHP James Paxton will be completely shut down from any throwing for two weeks dealing with a strained tendon in the middle finger of his left hand. Paxton was wearing a small splint on the finger and can do conditioning, just no throwing, until he’s re-examined.
Indians: Danny Salazar (5-1) will make his first career start against Seattle. He is currently sixth in the American League in strikeouts and has the highest strikeouts per nine innings ratio (12.04) in baseball.
Mariners: J.A. Happ (3-1) hasn’t lost in his last seven starts, but also does not have a victory since May 9. Happ allowed three earned runs in six innings last time out against Tampa Bay.